Hengameh Ghaziani was born on 20 May 1970 in Mashhad, Iran.
She has a BA in Human-Economic Geography from Islamic Azad University in Mashhad and Shahre-Rey, and has also a MA in Western Philosophy from San Francisco University.
Her acting career began in 2000 when she was cast in the movie Twilight, directed by Hassan Hedayt.
In addition to her artistic activity, she also translated Wilcomb E. Washburn's Red Man's Land/White Man's Law, a history book about the status of Native American.
In 2015 she started a band with herself as the singer, which performed in Vahdat Hall.
She has received two Crystal Simorgh awards for Best Actress at the Fajr International Film Festival, in 2007 for "As Simple as That" and in 2011 for "Days of Life"